Purpose: Our aim is to clarify the relationship between Overactive bladder syndrome (OAB) and severity of lower extremity ischemia by using Fontaine classification system.
Materials and Methods: Patients who were diagnosed with lower extremity AT were enrolled into the study. The Fontaine score of each patient was taken and all patients completed the validated Turkish version of OAB-V8 questionnaire. Body mass index, serum creatinine, blood urea nitrogen, cholesterol and fasting plasma glucose levels were measured. The patients were divided into two groups. Patients with OAB-V8 score above 8 were enrolled into group 1 and patients with OAB-V8 score under 8 were enrolled into group 2.
Results: At the end of study period, 322 patients were analyzed to be included study and 181 patients who met study inclusion criteria, were enrolled into the study. The patients with OAB ? 8 score (n: 79) and the patients with OAB < 8 score (n: 102) were compared. The mean age and the mean BMI were significantly higher in patients with OAB ? 8 (p=0.001 and p= 0.001, respectively). Also, HDL- cholesterol level was found significantly lower in patients in group 1 (p= 0.001). Multivariate regression analysis showed that presence of Fontain score ? Class 2b, age ? 60 years, BMI ? 30 kg/m2 and HDL-cholesterol levels < 60 mg/dL were predictive factors for OAB.
Conclusion: The present study has demonstrated that incidence of OAB was higher in patients with severe lower extremity ischemic symptoms, older age, high BMI and lower HDL-cholesterol level.
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